Jordan Hall, Room 1-17
Course director: Jeff Smith, Jordan Hall Rm 6-229, jss5y@virginia.edu
Texts:
BIOCHEMISTRY, C.K. Mathews and K.E. van Holde, Benjamin Cummings
Publishing Co., latest edition.
INTRODUCTION TO PROTEIN STRUCTURE, C. Brandon and J. Tooze, Garland Publishing Co., Second Edition (1999).
Examinations: There are 4 in-class examinations. Exams 1 - 3 will
begin at 8:00am; Exam 4 will be held at 8:30 am.
| T | 8/28 | Introduction/General Architecture of Biomacromolecules Lecture PDF | Nakamoto |
| R | 8/30 | Structure and Properties of Amino Acids and the Peptide Backbone Lecture PDF | Nakamoto |
| M | 9/3 | Primary and Secondary Structures in Proteins Lecture PDF | Nakamoto |
| T | 9/4 | Secondary Structure Prediction Lecture PDF | Nakamoto |
| R | 9/6 | Spectroscopy of Proteins Lecture PDF | Khorasanizadeh |
| M | 9/10 | NMR I Lecture PDF | Khorasanizadeh |
| T | 9/11 | NMR II Lecture PDF | Khorasanizadeh |
| R | 9/13 | Protein Folding and Kinetics Lecture PDF | Khorasanizadeh |
| M | 9/17 | Protein Folding and Kinetics II Lecture PDF | Khorasanizadeh |
| T | 9/18 | Spectroscopic Approaches to Protein Folding Lecture PDF | Khorasanizadeh |
| R | 9/20 | Review | |
| M | 9/24 | Exam I 2004 exam | |
| T | 9/25 | Electron Microscopy | Egelman |
| R | 9/27 | Membrane Protein Structure I Lecture PDF | Wiener |
| Membrane protein structure WWW site | |||
| M | 10/1 | Protein Evolution Lecture PDF | Pearson |
| Answers to student questions | |||
| T | 10/2 | Protein Domains/Morphology Lecture PDF | Pearson |
| R | 10/4 | Membrane Protein Structure II Lecture PDF | Wiener |
| M | 10/8 | Reading break | |
| T | 10/9 | Reading break | |
| R | 10/11 | Protein polymers - structure and assembly | Egelman |
| M | 10/15 | Protein polymerization - kinetics | Egelman |
| T | 10/16 | Crystallography I Lecture PDF | Wiener |
| R | 10/18 | Crystallography II | Wiener |
| M | 10/22 | Exam II 2004 exam | |
| T | 10/23 | Protein purification | Smith |
| R | 10/25 | DNA-Protein interactions I | Auble |
| M | 10/29 | DNA-Protein interactions II | Auble |
| T | 10/30 | Allosterism | Auble |
| R | 11/1 | Protein-Protein Interactions I | Auble |
| M | 11/5 | Protein-Protein Interactions II | Auble |
| T | 11/6 | Protein Dynamics Lecture PDF | Wiener |
| R | 11/8 | Enzyme Kinetics I | Nakamoto |
| M | 11/12 | Enzyme Kinetics II | Nakamoto |
| T | 11/13 | Protein Structure and Mechanism: Protein Ser/Thr Kinases Lecture PDF | Brautigan |
| Assigned Reading PDF | |||
| R | 11/15 | Protein Structure and Mechanism: Protein Tyr Kinases Lecture PDF | Brautigan |
| Assigned Reading | |||
| M | 11/19 | Exam III 2004 exam | |
| T | 11/20 | Protein Structure and Mechanism: Protein Tyr Phosphatases Lecture PDF | Brautigan |
| Assigned Reading | |||
| R | 11/22 | Thanksgiving break | |
| M | 11/26 | Thanksgiving break | |
| T | 11/27 | Protein Structure and Mechanism: Protein Ser/Thr Phosphatases Lecture PDF | Brautigan |
| Assigned Reading | |||
| R | 11/29 | Protein modification I - Acetylation Lecture PDF | Smith |
| M | 12/3 | Protein modification II - Deacetylation Lecture PDF | Smith |
| T | 12/4 | Protein modification III - Methylation Lecture PDF | Smith |
| R | 12/6 | Protein Modification - Misc. Lecture PDF | Smith |
| M | 12/10 | Exam IV 8:30 am 2004 exam | |
Last updated 158-Aug-2007