Recent Publications

Turner, C.M. and Adler, P.N. (1995) The in vitro morphogenesis of pupal wings. Mech. of Develop. 52:247-256.

Jones, K. H., Liu, J. and P. N. Adler (1996) Molecular analysis of EMS induced frizzled mutations in D. melanogaster. Genetics 142:205-215.

Park, W.J., Liu, J. and Adler, P.N. (1996).The Drosophila tissue polarity gene inturned acts cell autonomously and encodes a novel protein. Development 122:961-969.

Platero, J. S., Sharp, E.J., Adler, P.N. and Eissenberg, J.C. (1996). In vivo assay for protein-protein interactions using Drosophila chromosomes. Chromosoma 104:393-404.

Sharp, E.J., Abramova, N. A., Park, W.J. and Adler, P.N. (1997). The conserved HR domain of the Drosophila Supressor 2 of zeste and murine bmi-1 proteins constitutes a locus-specific chromosomal binding domain. Chromosoma, 106:70-80.

Adler, P.N.,Krasnow, R.E., and Liu, J. (1997). Tissue polarity points from cells of higher Frizzled levels toward cells of lower Frizzled levels. Current Biology 7:940-949.

Turner, C.M. and Adler, P.N. (1998). The actin and microtubule cytoskeletons have distinct functions in the morphogenesis of prehairs by pupal wing cells of Drosophila. Mechanisms of Development, 7: 181-192.

Adler, P. N., Charlton, J., and Liu, J. (1998). Mutations in the cadherin superfamily gene dachsous have a tissue polarity phenotype and affect frizzled signaling. Development 125: 959-968.

Taylor, J., Abramova, N. Charlton, J. and Adler, P. N. (1998). Van Gogh A new tissue polarity gene. Genetics 150: 199-210

Jeong, U., Kim, S.Y., Liu, J., Adler, P.N., Bae, E., Kim, J. and Park, W.J. (1999) The inturned protein of Drosophila melanogaster is a cytoplasmic protein located at the cell peripehry in wing cells. Developmental Genetics 25: 297-305.

Chae, J.W., Kim, M.J., Goo, J.H., Collier, S., Gubb, D., Charlton, J., Adler, P.N. and Park, W.J. (1999). The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family. Development, 126: 5421-5429.

Collier, S., Chan, H. Y. E., Toda, T., McKimmie, C., Johnson, G., Adler, P. N., O'Kane, C. and Ashburner, M. (2000). The Drosophila embargoed gene is required for larval progression and encodes the functional homolog of Schizosacchromyces Crm1. Genetics 155: 1799-1807.

Adler, P. N., Taylor, J. and Charlton, J. (2000). The Domineering Nonautonomy of frizzled and Van Gogh Clones in the Drosophila Wing is a Consequence of a Disruption in Local Signaling. Mech. Dev. 96: 197-207.

Geng, W., He, B., Wang, M. and Adler, P. N. (2000). The tricornered gene, which encodes the Drosophila NDR kinase is required to maintain the integrity of cellular extensions. Genetics 156:1817-1828.

Adler, P. N., Liu, J. and Charlton, J. (2000). Cell size and the morphogenesis of wing hairs in Drosophila. Genesis 28:82-91.

He, B. and Adler, P. N. (2001). Cellular Mechanisms in the Development of the Drosphila arista. Mechanisms of Development, Mech. Dev, 104:69-78.

Adler, P. N. and J. Taylor (2001).frizzled signaling: simple but not plane.Current Biology, 11, R233-236

Cong, J., Geng, W., He, B., Liu, J., Charlton, J. and P. N. Adler (2001). The furry gene of Drosophila is important for maintaining the integrity of cellular extensions during morphogenesis. Development, 128:2793-2802

Adler, P.N. and H. Lee (2001). Planar polarity and frizzledsignaling. Current Opinions in Cell Biology, 13:635-640.

He, B. and Adler, P. N. (2002). The genetic control of arista morphogenesis. Development, Genes and Evolution, 212:218-229.

Lee, H. and Adler, P. N. (2002). The inturned and fuzzy genes are required for the function of the frizzled pathway in the wing. Genetics 160:1535-1547.

He, B. and Adler, P. N. (2002). The frizzled pathway regulates the development of arista laterals. BMC Developmental Biology 2:7.

Fei, X., B. He and P. N. Adler (2002). The growth of Drosophila bristles and laterals is not restricted to the tip or base. J. Cell Sci, 115:3797-3806

Adler, P. N. (2002). Planar Signaling and Morphogenesis in Drosophila. Developmental Cell, Developmental Cell, 2, 525-535.

Lee, H, and P. N. Adler (2004). The grainy head transcription factor is essential for the function of the frizzled pathway in the Drosophila wing. Mech Dev. 121, 37-49.Fei, X., B. He and P. N. Adler (2002).

K. Emoto, Y. He, B. Ye, W.B. Grueber, P.N. Adler, L.Y. Jan, and Y.-N. Jan (2004). Control of Dendritic Branching and Tiling by the Tricornered-Kinase/Furry Signaling Pathway in Drosophila Sensory Neurons. Cell 119:245.

P. N. Adler, D. Stone and C. Zhu (2004). Inturned localizes to the proximal side of wing cells under the instruction of upstream planar polarity proteins. Current Biology, 14: 2046-2051.

Simon Collier, Haeryun Lee, Rosemary Burgess and Paul Adler. (2004). The WD40 repeat protein Fritz links cytoskeletal planar polarity to Frizzled subcellular localization in the Drosophila epidermis. Genetics in press.

Ying He, Xiaolan Fang, Kazuo Emoto, Yuh-Nung Jan, and Paul N. Adler. (2005) The Tricornered Ser/Thr Protein Kinase Is Regulated by Phosphorylation and Interacts with Furry during Drosophila Wing Hair Development. Molecular Biology of the Cell, in press