Jordan Hall, Room 1-17
Course Directors:
David Auble, Jordan Hall Rm 6-213, dta4n@virginia.edu
Jeff Smith, Jordan Hall Rm 6-229, jss5y@virginia.edu
Texts:
BIOCHEMISTRY, C.K. Mathews and K.E. van Holde, Benjamin Cummings
Publishing Co., latest edition.
INTRODUCTION TO PROTEIN STRUCTURE, C. Brandon and J. Tooze, Garland Publishing Co., Second Edition (1999).
Examinations: There are 4 in-class examinations. Exams 1 - 3 will
begin at 8:00 am; Exam 4 will be held at 8:30 am.
| T | 8/26 | Structure and Properties of Amino Acids and the Peptide Backbone - Lecture PPT | Nakamoto |
| Lecture Supplement | |||
| R | 8/28 | Structure and Function of Proteins - Lecture PDF | Nakamoto |
| M | 9/1 | Secondary Structure Prediction - Lecture PDF | Pearson |
| T | 9/2 | Protein Evolution I - Lecture PDF | Pearson |
| Answers to student questions | |||
| R | 9/4 | Protein Evolution II - Lecture PDF | Pearson |
| M | 9/8 | Protein Domains/Morphology - Lecture PDF | Pearson |
| T | 9/9 | Protein Structure Comparison/ Protein Morphology - Lecture PDF | Pearson |
| R | 9/11 | Spectroscopy of Proteins Lecture PDF | Khorasanizadeh |
| M | 9/15 | NMR I Lecture PDF | Khorasanizadeh |
| T | 9/16 | NMR II Lecture PDF | Khorasanizadeh |
| R | 9/18 | Review (NOTE: Additional Review Session: 4:00 in Jordan 1-17 on Friday 9/19) | |
| M | 9/22 | Protein Folding and Kinetics I Lecture PDF | Khorasanizadeh |
| T | 9/23 | Exam I previous exams | |
| R | 9/25 | Protein Folding and Kinetics II Lecture PDF | Khorasanizadeh |
| M | 9/29 | Spectroscopic Approaches to Protein Folding Lecture PDF | Khorasanizadeh |
| T | 9/30 | Electron Microscopy Lecture PDF | Egelman |
| R | 10/2 | Protein polymers - structure and assembly Lecture PDF | Egelman |
| M | 10/6 | Protein polymerization - kinetics Lecture PDF | Egelman |
| T | 10/7 | Crystallography I Lecture PDF | Wiener |
| R | 10/9 | Crystallography II Lecture PDF | Wiener |
| M | 10/13 | Reading Break | |
| T | 10/14 | Reading Break | |
| R | 10/16 | Membrane Protein Structure I Lecture PDF | Wiener |
| Membrane protein structure WWW site | |||
| M | 10/20 | Exam II previous exams | |
| T | 10/21 | Wiener | |
| R | 10/23 | Protein purification | Auble |
| M | 10/27 | DNA-Protein interactions I | Auble |
| T | 10/28 | DNA-Protein interactions II | Auble |
| R | 10/30 | Protein-Protein Interactions I | Auble |
| M | 11/3 | Protein-Protein Interactions II | Auble |
| T | 11/4 | Allosterism | Auble |
| R | 11/6 | Protein Dynamics Lecture PDF | Wiener |
| M | 11/10 | Enzyme Kinetics I Lecture PDF | Auble |
| T | 11/11 | Enzyme Kinetics II Lecture PPT | Nakamoto |
| R | 11/13 | Protein modification I - Acetylation Lecture PDF | Smith |
| F | 11/14 | Alternative Exam III time slot -info here- | |
| M | 11/17 | Exam III previous exams | |
| T | 11/18 | Protein modification II - Deacetylation Lecture PDF | Smith |
| R | 11/20 | Protein Modification - Misc. Lecture PDF | Smith |
| M | 11/24 | Protein Structure and Mechanism: Protein Ser/Thr Kinases Lecture PDF | Brautigan |
| Assigned Reading PDF | |||
| T | 11/25 | Protein Structure and Mechanism: Protein Tyr Kinases Lecture PPT | Brautigan |
| Assigned Reading | |||
| R | 11/27 | Thanksgiving Break | |
| M | 12/1 | Protein Structure and Mechanism: Protein Tyr Phosphatases Lecture PPT (updated) | Brautigan |
| Assigned Reading | |||
| T | 12/2 | Protein Structure and Mechanism: Protein Ser/Thr Phosphatases Lecture PPT (updated) | Brautigan |
| Assigned Reading | |||
| R | 12/4 | Review | |
| M | 12/8 | Exam IV 8:30 am previous exams | |
Last updated 4-December-2008