Projects
These projects originate in work started with the 2008 VGEM Team.
Genetic Attenuators
One of the main challenges in constructing synthetic biological systems is the inability to precisely regulate gene expression using artificial means. Tightly-regulated control of any given set of related transcriptional, translational and posttranslational events will require a combination of powerful strategies. Therefore, we are developing a library of transcriptional terminators intentionally redesigned to be functionally inefficient. Well-characterized, standardized terminators of various efficiencies should allow finely-tuned transcription attenuation and represents yet another step toward global biological control.
BioBrick Placeholder Sites
Assembling composite BioBricks is a tedious procedure that consumes valuable time. When assembling several BioBricks, it would be nice to be able to insert a BioBrick Placeholder that could later be used to insert a BioBrick part. BioBrick Placeholders accomplish this task by providing internal restriction sites compatible with the standard BioBrick restriction sites.